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KMID : 0360220120530020256
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Journal of the Korean Ophthalmological Society
2012 Volume.53 No. 2 p.256 ~ p.261
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The Effect of α1 -Adrenergic Blocker on Phacoemulsification
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Kim Eun-Kyoung
Chung Sung-Kun
Baek Nam-Ho
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Abstract
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Purpose: To evaluate the influence of α1-adrenergic blocker on phacoemulsification and the preventive effect of adrenergic blocker (AB) cessation before cataract surgery.
Methods: A prospective study was performed involving 92 eyes of 60 patients undergoing cataract surgery. Cases were divided into three groups: the use of α1AB with discontinuance before surgery (32 eyes), the use of α1AB with no discontinuance before surgery before surgery (31 eyes), and eyes not treated with α1AB (29 eyes). Clinical measurements and intraoperative parameters were compared among the three groups.
Results: Preoperative maximum pupil diameters of patients treated with α1AB were smaller than those of patients not administered α1AB (p = 0.027 and p = 0.018, respectively). The incidence of IFIS in the patients using of α1AB with discontinuance before surgery was 6.25%, and that in the patients using of α1AB with no discontinuance before surgery was 6.45%. There was no IFIS outbreak in the patients not using of α1AB. We noted no significant differences in absolute phaco time during phacoemulsification (p = 0.207) or in the three-month postoperative best corrected visual acuities among the three groups (p = 0.189).
Conclusions: Importantly, there appears to be a significant correlation between α1AB and the development of IFIS. To prevent complications of IFIS, surgeons should be vigilant in identifying patients taking α1AB, checking the degree of preoperative pupil dilatation and anticipating intraoperative difficulties. In addition, appropriate modifications should be made to the surgical strategy. Furthermore there was no benefit to discontinuing α1AB treatment before cataract surgery in the prevention of IFIS.
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KEYWORD
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α1-adrenergic blocker, Intraoperative floppy iris syndrome, Phacoemulsification
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